Endocrine Abstracts

Premature Ovarian Insufficiency (POI) is defined as impairement of ovarian function in women under 40 years, with a incidence between 1-4% in women of reproductive age. Among the major identified causes of Premature Ovarian Insufficiency, genetic factors related with X-chromosome are widely described. However, autosome defects are less common found and are related generally with genetic mutations instead of structural abnormalities of them. Thefor, we report a relevant case of...

Introduction: Overt hypothyroidism is associated with diastolic hypertension, but in subclinical hypothyroidism, data are inconclusive. HS tiroxina is a double-blind trial evaluating the effect of levothyroxine on blood pressure in patients with mild SH (TSH 5.0–9.9 mU/l and normal free T4) and moderate-to-high cardiovascular risk.Methods: We analized baseline data of the first 46 patients screened. Confirmatory thyroid function tests wer...

Introduction: Syndrome of Inappropriate Antidiuretic (SIAD) is the most frequent cause of hyponatremia in parenteral nutrition (PN) patients. Yet studies concerning SIAD therapy are lacking. Our objective was to describe SIAD treatment and determine pre-treatment predictors of failure to respond to fluid restriction (FR) and furosemide efficacy prediction in a group of patients with SIAD while receiving PN.Methods: Prospective, non-interventional, multic...